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shareholders

Significant shareholders (holdings greater than 3%):

Shareholder 30-Oct-20 % IC
Mr Richard Griffiths 21,443,828 25.74
Mr Robert Keith 12,310,924 14.78
Compagnie Odier SCA 9,134,690 10.97
Mr Robert Quested 7,860,279 9.44
Mallinckrodt 5,062,167 6.08
AstraZeneca 4,418,022 5.30
American Depositary Receipts 3,004,725 3.61

Number of securities in issue: 83,306,259 ordinary shares

Percentage of AIM securities not in public hands: 57.71%

Last updated: 31st December 2020